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Myxedema coma ppt

Myxoedema coma is the extreme manifestation of (usually untreated) hypothyroidism. It is one of a relatively small number of endocrine emergencies, and it is a rare, but potentially fatal disorder. It does not necessarily involve the presence of pretibial oedema or of coma. »In a patient who has untreated or undertreated hypothyroidism several. Myoxedema Powerpoint Of Presentation Coma. It is unclear what the optimal levels for serum TSH and thyroid hormones should be in this population A coma is a prolonged state of unconsciousness. In most patients hypothyroidism is a permanent condition requiring lifelong treatment. Powered by netvibes. Sep 15, 2011 · 1. Myxedema Coma Treatment Myxedema Coma Is A State Of Decompensatedhypothyroidism. A Person May Have PPT. Presentation Summary : Myxedema coma is a state of decompensatedhypothyroidism. A person may have lab values identical to a normal hypothyroid state, but a stressful even 28488744 Myxedema Coma - Free download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text File (.txt) or view presentation slides online

Myxedema coma, the extreme manifestation of hypothyroidism, is an uncommon but potentially lethal condition. Patients with hypothyroidism may exhibit a number of physiologic alterations to. Table I. Diagnostic Scoring System for Myxedema Coma* Thermoregulatory dysfunction (Temperature oF/ C) Points >95/35 0 89.6-95/32-35 10 <89.6/32 20 Central Nervous System Effects Absent 0 Somnolent/Lethargy 10 Obtunded 15 Stupor 20 Coma/seizures 30 Gastrointestinal Findings Anorexia/abdominal pain/constipation 5. Myxoedema coma, the extreme manifestation of hypothyroidism, is exceedingly rare due to the widespread availability of thyroid-stimulating hormone assay. It is an endocrine emergency associated with a high mortality rate. The hallmark presentation of myxoedema coma includes decreased mental status and hypothermia

Thyroidectomy scar - In patients with altered mental status, suggests myxedema coma as a potential cause A Swedish study, by Mourtzinis et al, found the rates of hypothyroidism and hyperthyroidism in patients with atrial fibrillation to be 5.9% and 2.3%, respectively, compared with 3.7% and 0.8%, respectively, in controls Myxedema coma is defined as severe hypothyroidism leading to decreased mental status, hypothermia, and other symptoms related to slowing of function in multiple organs. It is a medical emergency with a high mortality rate. Fortunately, it is now a rare presentation of hypothyroidism, likely due to earlier diagnosis as a result of the widespread.

Myxoedem

Powerpoint Presentation Of Myoxedema Com

  1. Myxedema is a term used synonymously with severe hypothyroidism.However, the term is also used to describe a dermatological change that can occur in hyperthyroidism and (rare) paradoxical cases of hypothyroidism.In this latter sense, myxedema refers to deposition of mucopolysaccharides in the dermis, which results in swelling of the affected area. One manifestation of myxedema occurring in the.
  2. Myxedema crisis is a severe life threatening form of decompensated hypothyroidism which is associated with a high mortality rate. Infections and discontinuation of thyroid supplements are the major precipitating factors while hypothermia may not play a major role in tropical countries. Low intracellular T3 leads to cardiogenic shock, respiratory depression, hypothermia and coma
  3. The 5% dextrose in 0.45% sodium chloride solution will treat hyponatremia and hypoglycemia associated with myxedema coma. Obtain blood specimens for arterial blood gas (ABG) analysis, complete blood cell count, chemistry profile, and thyroid function tests. Also obtain a urine specimen for urinalysis. Obtain an ECG and a chest X-ray
  4. ation of severe, longstandin
  5. Hypothyroidism - Free download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text File (.txt) or view presentation slides online. Hypothyroidis

Myxedema coma is the end stage of untreated or inadequately treated hypothyroidism. It has an estimated incidence of 0.22 per million per year. The clinical picture is often that of an elderly obese female, presenting in midwinter with increased lethargy, somnolence, and confusion. The presentation is one of severe hypothyroidism, with or. Myxedema coma, the most severe form of hypothyroidism, is rare. It may be caused by an infection, illness, exposure to cold, or certain medications in people with untreated hypothyroidism. Symptoms and signs of myxedema coma include Myxedema coma is profound decompensated hypothyroidism usually precipitated by stressors, and its occurrence in association with total thyroidectomy or metabolic disorders, such as diabetic ketoacidosis, is unusual. A 43-year-old Asian man with history of total thyroidectomy who was scheduled for a second radioactive iodine therapy presented to our hospital with decreased mental status and. Introduction. Myxedema coma, an emergency presentation of hypothyroidism, is well-known to be a life-threatening condition. 1 The occurrence of this disease is rare, with an estimated incidence of 0.22 per million per year in a previous European study. 2 Owing to its rarity, the clinical features associated with enhanced survival of this disease remain unclear

Ppt Myxedema Powerpoint Presentations and Slides » View

  1. death. Myxedema coma is a rare but severe complication of myxedema. It is a life-threatening complication with a mortality rate of 25-60 percent and tends to affect older adults. Symptoms of.
  2. Myxedema coma is a state of severe life-threatening hypothyroidism that is classically associated with decreased mentation. It is a clinical diagnosis, and no one specific laboratory value can establish the diagnosis. The typical myxedema coma case presents as an elderly woman with all the features of long-standing hypothyroidism but with stupor or coma and hypothermia
  3. View THYROID DISORDERS.ppt from NURSING 101 at Harvard University. 29/10/20 1 THYROID DISORDERS The thyroid gland secretes T3, T4 and thyrocalcitonin Secretion is controlled by TSH Hypothyroidism or. 29/10/20 24 Supportive therapy In severe hypothyroidism and Myxedema coma,.
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  5. g (warm O2, scalp/groin/axilla warm packs, NG lavage) Thyroxine (T4) 500 micrograms IV, then 50 mcg qd IV Add 25 mcg triiodothyronine (T3) PO.

Myxedema Coma Hypothyroidism Com

Ppt Myxedema-coma-ppt Powerpoint Presentations and

Myxedema Coma: Diagnosis and Treatment - American Family

Myxedema coma is a rare fatal condition as a result of long-standing hypothyroidism with loss of the adaptive mechanism to maintain homeostasis. Hypothyroidism due to any cause including autoimmune disease, iodine deficiency, congenital abnormalities, or medications like lithium and amiodarone, can precipitate myxedema coma if left untreated Myxedema coma is an illness that occurs primarily in females at a rate of 4:1 compared to men. It typically impacts the elderly at the age of greater than 60 years old, and approximately 90% of cases occur during the winter months. Myxedema coma is the product of longstanding unidentified or undertreated hypothyroidism of any etiology In the Rapid Review series, I briefly review the key points of a clinical review paper (or two). The topic this time: Severe hypothyroidism (aka myxedema coma) The papers: Bridwell RE, Willis GC, Gottlieb M, Koyfman A, Long B. Decompensated hypothyroidism: A review for the emergency clinician.Am J Emerg Med. 2021 Jan;39:207-212. doi: 10.1016/j.ajem.2020.09.062 PMID: 3303922

Myxedema coma is a rare syndrome that represents the extreme expression of severe, longstanding hypothyroidism. It is a medical emergency and, even with early diagnosis and treatment, the mortality can be as high as 60%. The name is somewhat a misnomer, as actual coma is rare. The syndrome includes decompensated hypothyroidism, central nervous. Myxedema coma is an infrequent life‐threatening complication of hypothyroidism 7. Myxedema coma may be part of the natural progression of hypothyroidism or may be triggered in patients with chronic hypothyroidism by conditions such as drug overdose, myocardial infarction, cerebral infarction, injury, or cold exposure with previously existing. Raionale: Myxedema coma (MC) is extremely rare but lethal in pediatric patients with hypothyroidism leading to altered mental status and hypothermia. But there is no clinical guideline for such cases. Patient concerns: A 6-year-old Chinese girl presented with coma and hypothermia preceded by pneumonia. Her lab results were: free thyroxin (T4) 4.18 pmol/L and thyroid-stimulating hormone (TSH.

What is myxedema coma. Myxedema coma occasionally called myxedema crisis, is a rare life-threatening clinical condition in patients with longstanding severe untreated hypothyroidism that represents severe hypothyroidism with physiological decompensation 1).The condition usually occurs in patients with long-standing, undiagnosed hypothyroidism and is usually precipitated by infection. Myxedema coma, a potentially lethal complication of hypothyroidism is frequently associated with abnormalities of respiratory control [2-4]. We report on three patients with profound myxedema, all of whom demonstrated another major form of respiratory dysfunction, obstructive sleep apnea

Myxedema coma occurs as a result of long-standing, un-diagnosed, or untreated hypothyroidism and is usually precipitated by a systemic illness. Thyroid hormone plays an important role in cellular metabolism. Long-standing hypothyroidism results in reduced metabolic rate and decreased oxygen consumption, which affects all organ systems Myxedema coma is a life-threatening manifestation of hypothyroidism associated with altered mental status, hypothermia, and symptoms related to the slowing of other organ systems. It can occur as a culmination of severe, longstanding hypothyroidism or be precipitated by acute stressors such as infection, myocardial infarction, cold exposure. Thyroid Emergencies 1. Acuz Pratama. Thyroid Emergencies Heidi Chamberlain Shea, MD Endocrine Associates of Dallas f Thyroid Trivia • Largest endocrine gland - 20 grams in adult - Each lobe • 2-2.5cm in width and thickness • 4cm in height - Isthmus • 0.5cm thick • 2cm height and width • Named for the relationship to the. Myxedema Coma is Rare in children, but lethal . Mostly case reports in children. Mortality reported for myxedema coma between 30-60%. Occurs in patients with SEVERE hypothyroidism. [ Zhu, 2017 ] Primary hypothyroidism accounts for >95% of cases of myxedema coma. ~5% of cases are due to pituitary or hypothalamic causes

Myxedema coma is a rare syndrome that represents the extreme expression of severe, long-standing hypothyroidism. It is a medical emergency and, even with early diagnosis and treatment, the. The diagnosis of myxedema coma was made based on the patient's clinical presentation and a score of 65 on the diagnostic scoring system published in 2014 by Popoveniuc et al. [].The typical characteristics of myxedema coma, including bradycardia, hypotension, and hypothermia, were absent in this case

  1. Myxedema coma Hypothyroidism is the opposite of hyperthyroidism; the thyroid gland does not secrete enough thyroxine to support normal metabolic needs. Hypothyroidism happens eight times more.
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  3. Myxedema coma nursing NCLEX review on the pathophysiology, causes, signs and symptoms, and treatment (medications and pharmacology). Myxedema coma is a life-..
  4. Myxedema coma is defined as severe hypothyroidism resulting in a decompensated metabolic state and mental status change. It is classically characterized by thickened, nonpitting edema of the skin diffusely associated with severe chronic hypothyroidism. The diagnosis of myxedema coma is a clinical diagnosis based upon history and physica
  5. ation of severe, longstanding hypothyroidism or be precipitated by acute stressors such as infection, myocardial infarction, cold exposure, and surgery in patients with poorly controlled.
  6. Myxedema coma precipitated by diabetic ketoacidosis after total thyroidectomy: a case report. Kim JJ, Kim EY J Med Case Rep 2019 Mar 4;13(1):50. doi: 10.1186/s13256-019-1992-. PMID: 30827279 Free PMC Articl
  7. Myxedema Coma • Rare condition in which an individual with long-standing hypothyroidism presents with life-threatening decompensation • Occurs in 0.1% of patients with hypothyoidism • Most common in older patients with underlying pulmonary or vascular diseas

Myxoedema coma: a forgotten presentation of extreme

The physical examination findings of myxedema coma will reveal the characteristic signs of hypothyroidism, and not being able to obtain patient's history, it is often very useful to search for of other signs that guide the diagnosis of myxedema coma such as a cervical scar (history of thyroid surgery), vitiligo, hyperpigmentation, ophthalmopathy Pretibial myxedema can appear before, during, or after the thyrotoxic state. Pretibial myxedema is not related to thyroid function. The onset of pretibial myxedema is most commonly seen 12-24 months after the diagnosis of Graves disease, but it may occur before or after the onset of thyrotoxicosis Myxedema Coma (SinaiEM) Mission Statement. To create and provide free, open-access, comprehensive curricula and develop instructional practices that serve as the gold standard in medical education. Non-affiliation Disclaimer Hypothyroidism is a common endocrine disorder resulting from a deficiency in thyroid hormone (Rev Endocr Metab Disord 2016 May 7 [Epub ahead of print]) It is imperative to distinguish primary hypothyroidism from secondary / tertiary hypothyroidism (Indian J Endocrinol Metab 2011;15:S99), as the causes are very different In severe hypothyroidism decompensation, myxedema crisis / coma, a life. • The diagnosis for myxedema coma is typically based off of the presence of mental status changes, hypothermia, and a precipitating event. • Classic ECG findings include sinus bradycardia, prolonged QTc, RBBB, low voltage, and T wave inversion • Patient presenting with myxedema coma should be treated with mineralocorticoids until adrena

ANTIPSYCHOTIC MEDICATION EFFECTS MIMICKING MYXEDEMA COMA AND SEPSIS. INTRODUCTION: Olanzapine (Zyprexa) is an atypical antipsychotic that affects the dopaminergic pathway and is commonly used in the treatment of schizophrenia and bipolar disorder. Common side effects include extrapyramidal syndrome, akathisia, hyperprolactinemia, weight gain. Myxedema coma [17] Myxedema coma is an extremely rare condition caused by the decompensation of an existing thyroid hormone deficiency and can be triggered by infections, surgery, and trauma. Myxedema coma is a potentially life-threatening condition and, if left untreated, is fatal in ∼ 40% of cases. [18] Clinical presentatio What points, concerning myxedema coma are correct ? A. Hypothermia is common B. Feeling warm may provoke myxedema coma C. Cause is - increase sensitivity to T. 3. and T. 4. receptors. D. Hyperfunction of adrenal glands is present E. Thyroid cancer #62 . All clinical signs are typical for acute thyroiditis except: A. Vomitin Myxedema coma is defined as severe hypothyroidism, which can lead to several complications, including but not limited to hypothermia, altered mental status, hypoventilation, and organ failure Quiz that contains NCLEX questions for myxedema coma. Myxedema coma is a complication of untreated or undiagnosed hyothyroidism. As the nurse taking care of a patient with hypothyroidism, it is important you know the typical signs and symptoms, causes, and treatments

PPT - Congenital Hypothyroidism Presenting with Myxedema

PPT causes of myxedema coma. Trauma, infections, HF, meds. Presentation of myxedema coma. Altered mental state (common); diastolic hypertension, hypothermia, hypoventilation. TX of myxedema coma. IV T4 (levothyroxine); 100-500mcg load; then 75-100mcg/day until able to take PO; Lower dose in frail or established CV disease Myxedema Coma. p. 1156. 500. The client may have a weight gain and slowing metabolism that can mimic the signs of getting older. Hypothyroidism. p. 1164. 500. Is it concerning to the nurse if the client has hypoventilation that can lead to cardiovascular collapse? Yes. Myxedema coma is a medical emergency. p.115 Untreated hypothyroidism increases morbidity and mortality. In the United States, autoimmune thyroid disease (Hashimoto thyroiditis) is the most common cause of hypothyroidism, but globally lack of iodine in the diet is the most common cause. The patient presentation can vary from asymptomatic disease to myxedema coma High-dose thyroid hormone replacement has been recommended for treatment of myxedema coma (MC) while questions of safety of the therapy and of efficacy of low-dose thyroid hormone replacement have not been systematically addressed. We treated 8 patients with MC in a period of 18 years,. Myxedema coma is a state of decompensatedhypothyroidism. A person may have lab values identical to a normal hypothyroid state, but a stressful event precipitates the myxedema comastate. PowerPoint Presentation Last modified by: ummar khurshid.

Myxedema coma. Myxedema coma is a rare syndrome that represents the extreme expression of severe, longstanding hypothyroidism. It is a medical emergency associated with high mortality rate. Treatment of myxedema coma. Supportive care. PowerPoint Presentation Last modified by The course of untreated hypothyroidism is one of slow deterioration, potentially leading eventually to myxedema coma and death. Dr. M. Alzaharna (2014) Hyperthyroidism & Thyrotoxicosis. PowerPoint Presentation Last modified by - hypothyroid (myxedema coma) - ETOH withdrawal/intoxication - anoxic encephalopathy 22 Metabolic Coma Signs and symptoms of toxic - metabolic coma - pupils small - narcotics - pupils large - tricyclics - nystagmus - dilantin, pcp - respiratory depression - narcotics - tremor / asterixis - uremia, etoh, hepatic 23 Locked-in. myxedema coma are treated with enteral LT4, with or without LT3, through a nasogastric tube, while, in many other countries, these treatments are more frequently given intravenously. In previous small case-series studies, the mortality rates of myxedema coma were 36% (4 of 11 patients), 52% (12 of 23 pa In myxedema coma the breathing slows, the person has seizures and blood supply to the brain is decreased. It can be triggered by cold exposure, infection, trauma or medications like sedatives or tranquilizers. What to do? 1. Suspect hypothyroidism long before any of these symptoms occur so it can be diagnosed and treated early

Hypothyroidism and Myxedema Coma Clinical Presentation

CONCLUSIONS: While myxedematous pleuro-peritoneal effusions are rare, they can be massive and contribute to prolonged respiratory failure. Reference #1: Gotyo N, Hiyama M, Adachi J, Watanabe T, Hirata Y. Respiratory failure with myxedema ascites in a patient with idiopathic myxedema. Intern Med. 2010;49 (18):1991-6 Myxedema. This rare, life-threatening condition is the result of long-term, undiagnosed hypothyroidism. Its signs and symptoms include intense cold intolerance and drowsiness followed by profound lethargy and unconsciousness. A myxedema coma may be triggered by sedatives, infection or other stress on your body

Thyroid emergencies

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Objective: We report 2 patients who presented with clinical symptoms of acute upper airway obstruction from presumed supraglottic myxedema and compare their clinical presentation, diagnosis, and management with previously reported cases.Methods: Clinical data, laboratory results, imaging, and procedure reports were reviewed for both cases. A literature search was performed in MEDLINE using the. SAN DIEGO — Myxedema coma, a rare but potentially fatal form of decompensated hypothyroidism, can be identified according to key clinical signs and successfully treated in most patients with 500. PPT Neurological syndromes in systemic diseases and general medicine. Marta Lipowska. Encephalopathy. •Brain pathology of varies origins (metabolic, degenerative, genetic, posttraumatic, ischemic, hypoxic) •Generally it affects large parts of the brain instead of leading to identifiable focal changes. •Often developes when the reason.

PPT - Endocrine NCLEX PN Practice Questions II PowerPoint

Myxedema Coma Symptoms, Treatment, Causes & Hypothyroidis

Myxedema coma. This is the decompensated state of severe hypothyroidism in which the patient is hypothermic and unconscious. Assessment and Diagnostic Findings. Hypothyroidism can be detected in many ways. Physical examination. The thyroid gland is inspected and palpated routinely in all patients. Serum thyroid-stimulating tests Myxedema coma (or myxoedema coma) is defined as severe hypothyroidism that leads to altered mental status and hypothermia, as well as hypoglycemia, hyponatremia and hypoventilation. It can be the end-point of severe, long-standing, untreated (or under-treated) hypothyroidism or can be a hypothyroidism crisis precipitated by infection.

PPT - Hypothermia PowerPoint Presentation, free download

Myxedema Coma 1. Extreme hypothyroidism. 2. Hypo metabolic state » Hypothermia, hypotension, bradycardia, hypoventilation, altered mental status. 3. Diagnosis requires a high degree of suspicion. 4. Treatment is supportive and also aimed at restoring euthyroid state Myxedema coma is a life-threatening expression of hypothyroidism in its most severe form. It occurs most often during the winter months in elderly women with long-standing, undiagnosed, or undertreated hypothyroidism. It may be precipiated by infection or other stresses, and the diagnosis must be suspected based upon the clinical presentation.. CATZ B, RUSSELL S. Myxedema, shock and coma. Seven survival cases. Arch Intern Med 1961; 108:407. Somwaru LL, Arnold AM, Joshi N, et al. High frequency of and factors associated with thyroid hormone over-replacement and under-replacement in men and women aged 65 and over. J Clin Endocrinol Metab 2009; 94:1342

Myxedema Coma-Hypothyroidism is a chronic systemic disorder characterized by the progressive slowing of body functions due to the lack of thyroid hormone-The most feared complication of hypothyroidism is myxedema coma, which represents a form of _(1) medical ppt online.blogspot.com contains lecture notes in most fields of medicine. Myxedema coma Septic Shock. Clinical Presentation Clinical presentation varies with type and cause, but there are features in common Hypotension (SBP<90 or Delta>40 What are the signs and symptoms of myxedema coma & what nursing care is needed if this occurs? NEED HELP TO WRITE YOUR ESSAY FROM SCRATCH? PLACE AN ORDER TODAY AND GET QUALITY AND 100% ORIGINAL PAPER Post navigation. Describe the clinical manifestations present in Mr. M LWW PPT Slide Template Master Author: Dale Gray Created Date: 2/15/2001 7:07:27 PM Document presentation format: On-screen Show Company: Wolters Kluwer Health - Lippincott Williams & Wilkins Other title Myxoedema coma is a rare and life-threatening illness the outcome of which has not been robustly studied in large numbers, partly due to its low incidence. Dutta and colleagues have explored outcome predictors in a developing country where access to thyroid function tests is more limited than in the Western world. Cardiovascular instability, reduced consciousness, persistent hypothermia, and.

A fatal case of myxedema coma - Peertechz Publication

Decompensated hypothyroidism (myxedema coma) 1 comment. A 45 year old brought in by EMS after being found unconscious and cyanotic. She has Celiac disease, [] Methemoglobinemia. 1 comment. Case A 58 year old woman is brought in by EMS with acute onset respiratory distress. Over the [ Myxedema coma is a severe form of hypothyroidism that most commonly occurs in individuals with undiagnosed or untreated hypothyroidism who are subjected to an external stress. Features are as.

Myxedema Coma or Crisis Treatment & Management: Medical

Myxoedema coma. In very rare cases, a severe underactive thyroid may lead to a life-threatening condition called myxoedema coma. This is where the thyroid hormone levels become very low, causing symptoms such as confusion, hypothermia and drowsiness. Myxoedema coma requires emergency treatment in hospital The manifestations of Myxedema Coma include hypothermia, hypotension, cardiac arrhythmias, and bradycardia followed by death. It is rarely seen in patients under the age of 50 and is usually the cause of death in elderly hypothyroid patients who have not succumbed to associated cardiovascular disease Myxedema crisis or coma, is a rare and potentially fatal condition caused by low levels of thyroid hormones produced by the thyroid gland. Symptoms of myxedema coma include fever, changes in mental status or behavior, and body swelling. Myxedema crisis can be treated and managed if it is diagnosed early. If it is not, it requires emergency treatment. Call 911 or go to the nearest Urgent Care. 4) Psychogenic coma is a diagnosis of exclusion. 5) Endocrine/exocrine disorders include thyroid storm, as well as myxedema coma. Table 2. Causes of AMS A - alcohol, arrhythmia T - trauma, temperature disorders E - endocrine/exocrine, I - infection electrolytes, encephalopathy P - psychiatric, porphyria, poison Non-pitting edema is usually harder to treat than pitting edema. Pitting edema is often due to extra water, so it responds well to elevation and diuretics. Non-pitting edema, on the other hand, is.

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Endocrine Emergencies - Medscap

medical ppt online.blogspot.com contains lecture notes in most fields coma, vomiting, diarrhea, jaundice. • Mortality rate reachs 30% even with treatment • It´s usually precipitated by acute illness, such as: - Stroke, infection,trauma, diabeic ketoacidosis, surgery, radioiodine treatment • Myxedema coma - Reduced level of. 1 Introduction. Myxedema coma (MC) is a rare but lethal clinical condition in patients with longstanding, severe, untreated hypothyroidism with an estimated incidence rate of 0.22 cases per million people per year. MC is a life-threatening emergency with mortality as high as 60%. MC in children is exceedingly rare with only few reported cases and limited therapeutic experience

Myxedema coma, occasionally called myxedema crisis, is a rare life-threatening clinical condition that represents severe hypothyroidism with physiological decompensation. [1, 2] The condition usually occurs in patients with long-standing, undiagnosed hypothyroidism and is usually precipitated by infection, cerebrovascular disease, heart failure. Amiodarone is a class III antiarrhythmic drug often used to treat supraventricular and ventricular arrhythmias with high efficacy. Amiodarone is associated with thyroid dysfunction, which can lead to myxedema coma (MC) in undiagnosed cases. Amiodarone-induced MC is a life-threatening condition that presents a complex diagnostic challenge to emergency physicians Myxedema coma is a life-threatening complication of hypothyroidism, usually occurring in patients with a long history of hypothyroidism. Its characteristics include coma with extreme hypothermia (temperature 24° to 32.2° C), areflexia, seizures, and respiratory depression with carbon dioxide retention hypothyroidism case presentation ppt. May 22, 2021 ; 1 minute read. Myxedema coma is the term given to the most severe presentation of profound hypothyroidism and is often fatal in spite of therapy. Decompensation of the hypothyroid patient into a coma may be precipitated by a number of drugs, systemic illnesses (eg, pneumonia), and other causes. It typically presents in older women in the winter months and is associated with signs of hypothyroidism.

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Myxedema coma is characterized by nonresponsiveness, low body temperature (hypothermia), and respiratory depression. This condition is commonly precipitated by intake of sedating drugs, cold exposure, or infection and occurs most often in elderly women. Cretinism Myxedema coma: pathophysiology, therapy, and factors affecting prognosis. Med Clin North Am . 1995;79(1):185-194. Dutta P, Bhansali A, Masoodi SR, et al. Predictors of outcome in myxedema coma: a study from a tertiary care centre Definition. Hypothyroidism - also called underactive thyroid - is the most common thyroid disorder. It happens when your thyroid gland doesn't produce enough thyroid hormone, which is essential because thyroid hormone helps regulate important body processes, such as your metabolism. But with low thyroid function, these body processes slow.